Wednesday, November 28, 2012

Daily Business Update

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Daily Business Update


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Wed. Nov. 28, 2012

AMSC is cutting its workforce by 25 percent

AMSC, a Devens company that provides technology and products to wind energy companies and power grid operators, said Wednesday that it has reduced its workforce by 25 percent, a move that will leave it with a global headcount of 340 employees. A call to the company seeking additional details was not immediately returned. AMSC added that it expects that today’s action will reduce its annualized expenditures by $10 million and will lower its annualized operating expense.

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Ironwood’s drug for irritable bowel syndrome with constipation gets regulatory approval in Europe

Ironwood Pharmaceuticals Inc. of Cambridge and its European partner Almirall S.A. said Wednesday that Ironwood’s drug for irritable bowel syndrome with constipation has been approved by European regulators. That same drug is about to go onto the US market, following approval by the Food and Drug Administration earlier this year. According to a recent Globe story, irritable bowel syndrome, or IBS, afflicts 30 million to 40 million Americans. Given the number of people affected, the drug has the potential to be a blockbuster, ringing up annual sales of $1 billion or more.

FDA will review a drug candidate for kidney cancer from AVEO and Astellas

AVEO Oncology, a Cambridge-based cancer therapeutics company, and its Japanese partner Astellas Pharma Inc. said Wednesday that federal regulators have agreed to review its drug candidate for kidney cancer. In a press release, the companies said that the Food and Drug Administration has accepted their new drug application for tivozanib, a treatment for patients with advanced renal cell carcinoma, or kidney cancer.

Selecta Biosciences and Sanofi sign global collaboration

Selecta Biosciences Inc., a Watertown biopharmaceutical company specializing in synthetic vaccines and immunotherapies, said Wednesday that it has entered into a strategic global collaboration with Sanofi SA, the French drug maker that recently bought Cambridge-based Genzyme.

HFF closes $106.7m sale of four office buildings in Boston’s Seaport District

HFF, a provider of commercial real estate and capital markets services, said that it has closed the $106.75 million sale of a portfolio of four office buildings in the Fort Point neighborhood of Boston’s Seaport District. HFF said it exclusively represented the seller, Brickman Associates, and procured the buyer, DivcoWest Properties. The portfolio is made up of office buildings at 300 A St., 313 Congress St., 330 Congress St., and 51 Sleeper St.

Lawyers to offer lessons on how to open a medical marijuana dispensary in Massachusetts

Massachusetts and Colorado attorneys are planning a series of seminars aimed at helping potential patients and business owners understand Massachusetts’ recently passed medical marijuana law. The attorneys will explain the process of applying for, opening, and running a medical marijuana business, including sharing best practices from Colorado and other states. The first seminar, scheduled for 6 to 8 p.m., Thursday, at Cambridge Community Center, 5 Callender St., Cambridge, will also cover how people with debilitating health conditions can become state-legal medical marijuana patients.

Anthropologie to open store at new Chestnut Hill Square shopping center

Upscale women’s clothier Anthropologie is the latest tenant to sign on to the Chestnut Hill Square, a new shopping center under development on Route 9. Anthropologie will join the popular grocery store Wegmans, Equinox Fitness Club, Brio Tuscan Grille, Seasons 52, Century Bank, Francesca’s Collections, Red Mango, and other specialty shops and restaurants at the 340,000 square foot project currently under development. All of those stores and restaurants are scheduled to open in the fall of 2013.

Auction will feature fixtures from Locke-Ober, the famous Hub restaurant that recently closed

Local landmark restaurant Locke-Ober may have shut its doors, but on Dec. 7, Bostonians will have the chance to bid on parts of it to keep. The Paul E. Saperstein Co., a full-service auction and appraisal firm that is also known as Pesco, announced this week that it will auction off decor, furniture, restaurant and bar equipment, and fixtures from the cafe, which closed in October after 137 years in business. Everything from china and chandeliers to a wood-carved pool table and antique-style moldings will be auctioned.

Mirbeau Inn & Spa is coming to the Pinehills

Pinehills LLC, which operates the Pinehills master-planned community in Plymouth, said that Mirbeau LLC has purchased six acres on the property to open a 50-room Mirbeau Inn & Spa.

Peptide therapeutics firm Rhythm gets $8m from Pfizer Venture Investments

Rhythm, a Boston biotechnology company developing peptide therapeutics to treat such metabolic diseases as obesity and diabetes, said it has raised $8 million from Pfizer Venture Intestments, the venture capital arm of the drug company Pfizer and a new investor in Rhythm. That additional $8 million completes a $33 million Series B financing. The round had participation from existing investors MPM Capital, New Enterprise Associates, Third Rock Ventures, and Ipsen. This additional financing brings the total capital raised by Rhythm to $73 million.

WBUR acquisition would bring its radio programming to Martha’s Vineyard and much of Nantucket and Cape Cod

WBUR, a Boston public radio station, said Tuesday that it has agreed to acquire the license to broadcast its programming on the 92.7 FM radio signal in Tisbury, a move that should expand WBUR’s geographical reach and bring its programming to listeners on Martha’s Vineyard and most of Cape Cod and Nantucket, as well as Southeastern Massachusetts, by early next year. The seller is Aritaur Communications, which owns WMVY, a commercial FM radio station whose play list includes the likes of Neil Young, Stevie Ray Vaughan, and Norah Jones.

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